Low white blood cells and platelets at the same time, that is, the number of both white blood cells and platelets are below the normal range, in clinical low white blood cells and platelets at the same time can be divided into two categories of diseases, the first category is other diseases caused by the reduction of white blood cells and platelets, common are acute infections, such as acute respiratory tract infections, such as influenza virus, in this case, acute respiratory tract infections may cause white blood cells and platelets number A simultaneous decrease in platelet count. If the patient takes certain antipyretic drugs, such as ibuprofen and fenpropathrin, it is more likely that the white blood cells and platelets will decrease at the same time. The second category is that the simultaneous decrease of leukocytes and platelets caused by blood system diseases is very common, the most common ones are aplastic anemia, myelodysplastic syndrome, paroxysmal sleep hemoglobinuria, and more serious iron deficiency anemia and megaloblastic anemia, all of which can cause the simultaneous decrease of leukocytes and platelets.