Small platelet volume and width may be normal or caused by aplastic anemia, leukemia, infection, primary thrombocythemia and other diseases.
1. Small mean platelet volume is not specific to a particular clinical disease, but can be caused by a variety of conditions, such as primary thrombocythemia, which requires treatment with drugs such as hydroxyurea. Therefore, if the platelet count is normal, it is generally not necessary to consider whether the change in mean platelet volume is a problem.
2. The small width of platelet distribution indicates that the homogeneity of platelet volume is better, and in this case, it is also necessary to check whether there is any change in the number of platelets. If only these two tests are small, it may be a normal phenomenon, does not affect the normal function, usually do not need to deal with.
3. If the test is also accompanied by abnormal platelet count, a high count may indicate chronic granulocytic leukemia, primary thrombocythemia, secondary thrombocythemia caused by splenectomy or trauma, etc. A low count is commonly associated with infections, leukemia, aplastic anemia, and thrombotic thrombocytopenic purpura, and drug-immune thrombocytopenic purpura.
Therefore, the diagnosis of specific diseases should be completed under the guidance of a physician.