Coughing up lumps and lumps of yellow sputum may be due to common cold, pneumonia, bronchial dilatation, etc. Different treatments should be taken according to different causes, mainly antibacterial treatment and expectorant treatment, turning over and patting the back to promote the discharge of sputum, and can be combined with nebulization treatment. 1. Antibacterial treatment (1) Cephalosporins (cefadroxil, etc.), amoxicillin, etc. can be used for common cold combined with bacterial infection. (2) Bacterial pneumonia can choose penicillin, cephalosporin (cefaclor, etc.), mycoplasma pneumonia with macrolides (roxithromycin, etc.), viral pneumonia with antiviral therapy. (3) When bronchiectasis is combined with bacterial infection, coughing yellow sputum, sputum culture can be done to choose sensitive antibacterial drugs, postural drainage sputum discharge is sometimes more effective than antibacterial treatment, and is often the preferred method. If the combination of hemoptysis should be timely medical care. 2. Expectorant treatment: sputum can be thickened with yellow sputum, such as aminoglutethimide, bromhexine, and so on. 3. Nebulization therapy: for thick mucus, commonly used acetylcysteine and so on. Coughing up a pile of yellow sputum may also have other reasons, it is recommended to go to the hospital in time to identify the cause of the disease and targeted treatment. All of the above medications should be used under the guidance of a doctor, avoid self-medication.