The efficacy of temesartan 20mg and 40mg is the same, only the difference in drug dosage. Timosartan is a long-acting antihypertensive drug commonly used in the clinic, which can be used for the treatment of essential hypertension and the reduction of cardiovascular risk; the difference between 20mg and 40mg drugs is the difference in drug dosage, and it plays the same effect, both of which can lower blood pressure and reduce cardiovascular risk. Adverse reactions: dizziness, headache, fatigue, nausea and vomiting, cough and other adverse reactions can occur when taking this drug. Precautions: patients with impaired renal function should use this drug should be regularly monitored blood potassium, blood creatinine, mild or moderate hepatic impairment of patients should not exceed 40mg daily dosage. not recommended and ACE inhibitors used at the same time. Contraindications: It is contraindicated in patients who are hypersensitive to the components of the product, in mid to late pregnancy, in patients with obstructive biliary tract disease, and in patients with severe hepatic impairment. Not to be used simultaneously with Aliskiren in patients with diabetes mellitus or renal insufficiency. Timosartan drug should be used in strict accordance with the instructions of the doctor, if discomfort occurs during the administration of the drug, you should immediately consult a doctor.