Laparoscopic cholecystectomy (LC) has been accepted by modern surgery and has become the “gold standard” in the surgical treatment of benign gallbladder diseases. However, the use of laparoscopic techniques for the treatment of common bile duct lesions requires high operating techniques, relatively long operation time, and corresponding lumpectomy instruments, so laparoscopic treatment of common bile duct diseases is not common at present, and most of them still use traditional open surgery. In the past 3 years, we have performed laparoscopic cholecystectomy choledochotomy combined with choledochoscopic stone extraction and one-stage bile duct suture or T-tube placement in 84 cases of gallbladder stones combined with common bile duct stones with good results. In this regard, we summarize the laparoscopic treatment of this disease. Gallbladder stones combined with intra- and extrahepatic bile duct stones are relatively common in biliary surgery, and the traditional treatment methods include open cholecystectomy choledochotomy combined with choledochoscopic stone extraction, or cholecystectomy combined with duodenoscopic papillary sphincterotomy for stone extraction. However, in the last decade or so, laparoscopic cholecystectomy combined with preoperative or postoperative duodenoscopic papillary sphincterotomy for stone extraction, or laparoscopic cholecystectomy combined with choledochotomy for stone extraction have provided newer minimally invasive treatment methods for such diseases. With the continuous improvement of people’s living standard, the popularization of laparoscopic technology, the accelerated development of multi-functional laparoscopic instruments, the continuous improvement of laparoscopic operation level of professional physicians, and the increasing accumulation of surgical experience, the advantages of less trauma, faster recovery, better efficacy and cosmetic appearance of surgery make the use of minimally invasive techniques such as laparoscopy, duodenoscopy and choledochoscopy to treat gallstone disease become the modern minimally invasive treatment of biliary surgery. The use of minimally invasive techniques such as laparoscopy, duodenoscopy and choledochoscopy has become a hot spot in modern biliary surgery. Clinical practice shows that the majority of preoperatively diagnosed common bile duct stone cases can be removed by first laparoscopic cholecystectomy and choledochotomy, and even if there are residual stones in the bile duct after surgery, they can be removed by choledochoscopy via T-tube sinus tract or liquid electrolysis after 6-8 weeks; the indications for this procedure should be theoretically the same as open common bile duct exploration. Of the 84 patients with this disease in our center, 22 had a history of upper abdominal surgery, 6 of which were repeat biliary surgery, which was listed as a contraindication to laparoscopic biliary exploration in previous textbooks or reference books. After careful preoperative examination, discussion, and careful intraoperative operation, although the operation time was slightly longer, all of them completed the operation under laparoscopy and recovered quickly after the operation; after the postoperative T-tube clamping, only a soft rubber tube about 5-8 cm long was left outside the patient’s abdominal wall, without wound infection, pain and other manifestations, and did not prevent the patient’s work, study and daily life. Therefore, we believe that laparoscopic cholecystectomy with common bile duct exploration (LCBDE) can solve cholelithiasis and common bile duct stones by the same minimally invasive means while removing the gallbladder, which not only maintains the integrity of the sphincter of Oddi but also does not increase the complications of open surgery, and has many benefits of laparoscopic cholecystectomy; in addition, laparoscopic common bile duct dissection and lithotomy with T-tube drainage provides postoperative treatment for biliary tract In addition, laparoscopic choledochotomy and T-tube drainage provides a minimally invasive way to treat gallstone diseases such as residual stones and multiple stones inside and outside the liver. With the increasing popularity of laparoscopic technology and the improvement of surgeons’ experience and skillful laparoscopic skills, the LCBDE procedure will be commonly performed and become an effective means of managing common bile duct stone disease, and is expected to become the “gold standard” for surgical treatment of common bile duct stones.