The normal value of routine blood leukocytes is (4.0-10.0)×10^9/L. If the value is high, it is called leukocytosis, which is usually caused by emotional stress, full meal, cold, strenuous exercise, or physiological factors such as women in menstruation, ovulation, pregnancy, etc. It is also seen in newborns, which is a normal phenomenon and can be reviewed regularly. In addition, it may also be related to other factors, such as drug factors, infections, blood system diseases, etc. 1, drug factors: if the patient long-term application of prednisone, methylprednisolone, betamethasone and other glucocorticosteroids, the phenomenon of high white blood cells in the routine blood test may occur, you need to go to the hospital to carry out relevant tests, according to the results to consider whether the need to adjust the drug regimen; 2, infection: the patient is affected by The phenomenon of leukocytosis may also occur after patients are infected with bacteria or viruses such as Staphylococcus aureus and Streptococcus pneumoniae. Penicillin G, amoxicillin and other penicillins, or cephalosporins can be used for treatment. Relevant examinations are needed to clarify the specific causes for targeted treatment; 3. Blood system diseases: If the patient suffers from leukemia, myelodysplastic syndrome and other blood system diseases, it may also lead to the phenomenon of high white blood cells. It is recommended that patients further undergo blood biochemistry, bone marrow biopsy and other examination items to clarify the diagnosis, and timely drug therapy, immunotherapy, surgery, etc., according to the specific circumstances, in order to avoid aggravation of the disease; 4, liver disease: patients with high white blood cells may also be related to liver diseases such as liver abscess, explosive hepatitis, heavy hepatitis, liver cancer, etc., due to necrosis of some tissues of the liver, which can lead to a large differentiation of lymphocytes and an increase in bone marrow granulocytes, resulting in high leukocytes; 5. Other: If the patient suffers from large burns, severe trauma, or myocardial infarction, etc., this can lead to partial tissue damage and destruction of blood cells, resulting in an increase in leukocytes. In addition, after acute hemorrhage, malignant tumors, etc. may also lead to high white blood cells. Patients are advised to take appropriate resuscitation measures and treatment according to the specific etiology.