Nipple pain when touching is not necessarily cancer. Breast cancer in the terminal stage may cause nipple pain when touching because the lump is too big or the tumor compresses the nerves, but it is not a common or typical manifestation. This phenomenon is common in women, but it cannot be ruled out that some male patients have this kind of symptom due to pathological factors or some life factors. Nipple tenderness may be caused by physiological factors, but also can be seen in breast disease, skin disease and other pathological factors, as well as other physical factors. Physiological factors: women’s menstruation, pregnancy and breastfeeding, adolescent development, hormone level changes in the body, may lead to nipple pain, often accompanied by breast swelling and pain and other phenomena. This kind of situation usually wait for the hormone level to return to normal, the symptoms can disappear, without special treatment. Second, pathological factors: 1, skin diseases: such as rashes, dermatitis, etc., may lead to localized nipple tenderness, accompanied by redness, itching and other symptoms, may be related to the environment, skin care products and other stimuli on the skin. It may be related to skin irritation caused by environment and skin care products. It is recommended to stay away from allergens, use mild and allergy-relieving skin care products, and use drugs such as loratadine and mupirocin ointment as prescribed by doctor for treatment if necessary. 2. Breast diseases: Heredity, life stress, infection and other factors may lead to breast diseases, such as mastitis, breast hyperplasia, and breast tumors, which may lead to nipple pain at the touch. In case of breast cancer, patients may have symptoms such as breast lumps, nipple pain and overflow, and orange peel-like changes in breast skin. The cause can be treated by life management, medicine, surgery and radiotherapy; 3. Other: If the child has Candida albicans infection when breastfeeding, it may be infected to the mother, resulting in pinprick tenderness in the nipple, accompanied by burning sensation, reddening of the nipple and other uncomfortable symptoms. At this time, it is recommended to suspend breastfeeding, timely medical treatment. Other factors: 1, life factors: such as underwear is too tight, there are foreign objects, etc., so that the nipple skin is worn, nipple will appear a touch of pain, it is recommended to choose comfortable clothing, for the broken wounds attention to disinfection; 2, behavioral factors: breastfeeding women may be feeding the child due to inappropriate posture, leading to nipple in the child breastfeeding nibbled, can also lead to nipple skin breakage, nipple will appear a touch of pain. The nipples may hurt when they are touched. It is recommended to choose the correct breastfeeding posture to avoid aggravating the injury, and pay attention to the cleanliness and hygiene of the nipple after breastfeeding to avoid causing infection. To summarize, there are many reasons why male or female nipples hurt when touched, and it is not necessarily cancer. It is recommended to go to the hospital in time for relevant examination after symptoms appear, to clarify the cause of the disease, and then carry out corresponding and effective treatment for the cause.