Ebastine and loratadine, both commonly used in allergic rhinitis treatment, the principle of action is similar, the overall efficacy varies from person to person, need to be evaluated after use according to the symptoms of changes in the differences. 1. Ebastine belongs to other classes of antihistamines, and is used clinically for the treatment of allergic rhinitis, urticaria, and pruritus. Taking the drug may cause dry mouth, headache, drowsiness and other adverse reactions, contraindications are not clear, pregnant and lactating women should be cautious, can be used for children over 2 years old. 2. Loratadine belongs to the piperidine antihistamine class of drugs, used in the treatment of allergic rhinitis, chronic urticaria, allergic conjunctivitis and other diseases. Taking the drug may cause adverse reactions such as dry mouth and headache. It is contraindicated in allergic individuals and used with caution in lactating women. It can be used in children over 6 years of age. When allergic rhinitis occurs, do not blindly choose medication on your own, but it is recommended to standardize the use of medication under the guidance of a physician.