The ability to recover from antinuclear antibody 1:320 is related to the disease that causes it to be elevated. Mild infectious diseases can usually be cured, while rheumatic and immunological diseases and tumor diseases are difficult to be cured. The normal reference value for quantitative antinuclear antibodies varies according to the test method and the test standard, but is usually less than 1:100. Therefore, 1:320 is on the high side. Significantly elevated quantitative antinuclear antibodies are most commonly found in rheumatic diseases, but are also occasionally found in infectious diseases, neoplastic diseases, and in normal elderly people. 1. Rheumatic immune diseases: antinuclear antibody quantification can be seen in rheumatic immune diseases, this disease is usually a chronic disease, the condition of the long-term development of the clinic is generally difficult to be cured. 2. Part of the population suffering from infectious diseases may also cause elevated antinuclear antibodies. Generally, mild illnesses such as colds and upper respiratory tract infections will recover as the disease recovers. This type of disease can be cured by treatment. 3. Quantitatively elevated antinuclear antibodies can also be caused by neoplastic diseases, which are difficult to treat. 4. Elevated quantitative antinuclear antibodies may also occur in some normal elderly people, and generally do not require treatment if there are no uncomfortable symptoms. If the quantitative antinuclear antibodies are significantly elevated, it is necessary to go to the rheumatology and immunology departments of regular hospitals in a timely manner, and follow the doctor’s instructions for diagnosis and treatment.