Cerebral thrombosis can make patients stupid, mainly in temporal lobe infarcts, especially hippocampal lesions, which are related to human intelligence and memory. The hippocampus is related to intelligence and memory. When the hippocampus is damaged, a person can experience cognitive impairment, which can manifest as stupidity. Cerebral thrombosis causing stupidity can also be seen in repeated cerebral thrombosis leading to vascular dementia and cognitive decline in patients. The treatment of cerebral thrombosis causing stupidity is mainly based on active treatment of cerebrovascular disease, and if necessary, it can be combined with drugs to improve brain metabolism and nourish brain cells, such as cerebroprotein hydrolysate tablets, olanzapine, piracetam, etc. If necessary, patients can also be given oral lithospermidine A or donepezil hydrochloride, but the clinical effect is not particularly satisfactory, because lithospermidine A and donepezil hydrochloride are mainly for the treatment of cognitive decline caused by Alzheimer’s disease.