Atrophic gastritis with intestinal chemosis accompanied by mild heterotrophic hyperplasia may be a precancerous lesion, which can be treated with medication to slow down the progression of the disease and reduce the risk of cancer. Patients with chronic atrophic gastritis usually have symptoms such as epigastric discomfort, fullness, pain, loss of appetite, acid reflux, heartburn, etc. Patients with serious condition will develop heterozygous hyperplasia and intestinal chemosis in the later stage, which will have a certain risk of cancer. The treatment of patients is mainly to remove the cause of the disease, adverse factors, such as quitting smoking and alcohol, if there is Helicobacter pylori infection, you can take omeprazole, amoxicillin, metronidazole, bismuth potassium citrate and other drugs for treatment. If it is caused by other reasons, patients can take drugs to protect the gastric mucosa such as aluminum thioglycollate and Rebapatide, as well as drugs to promote gastrointestinal peristalsis such as domperidone and mosapride to prevent bile reflux. Patients should also undergo regular review to monitor the change of the condition, and undergo early surgical treatment if there is any discovery of cancer cells. It is recommended that patients should seek medical treatment in time and actively carry out treatment under the guidance of doctors. Drugs should be used under the guidance of professional physicians, and should not be used arbitrarily by oneself.