If a woman has edema in her ankle, and the edema is depressed edema, that is, a pit when pressed, the treatment needs to be judged according to the actual situation.1. If an ankle appears in the above-described situation, it is possible that it is a trauma, mosquito bite or gouty nodule, or a woman has poor vascular reflux in the lower limbs, lower limb thrombosis, and it needs to be differentiated and diagnosed from the appearance and the ultrasound of vasculature of the lower limbs, applying medication in order to reduce the treatment. Application of drugs to reduce swelling treatment; 2, excluding the local lesions, is a systemic lesion, systemic lesions may have a special situation is the female menstrual period, the body’s hormone level disorders, may occur during the menstrual period of edema, the need to check the body’s hormone level to assist in diagnosis, in order to facilitate the treatment; 3, to exclude the above, is a systemic disease caused by bilateral ankle depression of edema. The above cases are ruled out, and then there are systemic diseases causing bilateral ankle depression edema, such as heart disease, kidney disease, thyroid disease, rheumatism disease and endocrine system disease, and so on.