Gout is a crystal-associated arthropathy caused by urate deposition. Sudden onset of single joint redness, swelling and heat pain is a common clinical manifestation of acute gout attacks and should be treated accordingly. The treatment of acute gout attack mainly adopts drug therapy. It mainly includes 1, non-steroidal anti-inflammatory drugs: such as indomethacin diclofenac, etc. 2, colchicine: is the traditional drug for the treatment of acute gout attack, but it is less used now because of its more adverse reactions. 3, glucocorticoids: the treatment of acute gout is effective, small and medium doses, oral, intramuscular injection or intravenous injection can be, after discontinuation of the drug, the symptoms are easy to “rebound”. After the acute joint pain attack is relieved, you may need to use uric acid production inhibitors or uric acid excretory drugs. In addition, gout stones can be treated surgically if they are large and affect the appearance and function of the joints or if the joints are severely deformed. It is important to note that lifestyle and dietary habits of gout patients are the basis for long-term treatment of gout. It is important to avoid a high purine diet, to avoid high purine foods such as animal offal and seafood, to maintain an ideal body weight, to drink more water, and to keep bowels and stools open. In addition, patients should have a correct understanding of the disease, eliminate fear, establish confidence in treating the disease, and understand the importance of following medical advice and regular follow-up. In conclusion, patients with gout-induced ankle pain should use drugs to relieve acute attacks in a timely and adequate amount during the acute phase, and then adhere to systematic and standardized preventive treatment measures to ensure the stability of the disease and avoid frequent acute attacks.