Intra-articular sodium hyaluronate injection therapy is generally available in cases of chondromalacia patellae or when there is mild to moderate cartilage damage in the knee and other joint solutions. The injection protocol is once a week, with the average drug being injected five times. The number of injections can be reduced for a very few species with high molecular weight and high dosage (there will be a note on the instruction sheet). The injection of sodium hyaluronate is supposed to feel like this: it hurts a little when the needle goes through the joint capsule, like a shot in the buttocks. However, it should not hurt when the needle enters the joint and starts to push the drug until it is finished. If it hurts significantly during the pushing process, it means that the needle tip is in the synovial membrane and the drug is hitting the synovial membrane, not in the joint. This not only hurts when pushing the drug, but also after pushing the drug, because the tension in the synovial membrane where the drug is wrapped is higher than before pushing the drug, and it will also affect the injection effect. Under normal circumstances, there will be some mild pain or discomfort in the knee joint after the injection, which will disappear 1 to 3 days after the injection and should be fully recovered by the next injection. If the knee joint is very painful after the injection and lasts for a long time, it is abnormal. If after the injection, the process is all smooth and the knee is still very significantly swollen, it means you may be allergic to the drug and it is best to avoid it next time. If your sensation during and after the injection is abnormal, you can compare the injection with a different doctor.