Diabetes mellitus with edema may be a result of kidney damage caused by a longer history of diabetes mellitus, called diabetic nephropathy, which may be accompanied by other manifestations such as proteinuria and reduced albumin in the blood, which can be clinically identified by liver and kidney function and urine routine. Diabetes mellitus with edema may also be caused by peripheral vascular and neuropathy of the lower extremities. In addition to swelling of both lower extremities, it may be accompanied by numbness, coldness and pins and needles pain in both lower extremities and feet, which can be clinically identified by the examination of arteriovenous vascular ultrasound and neurophysiology of both lower extremities. If you have diabetes with leg swelling, you should go to the hospital in time to improve the relevant tests and take medication as early as possible.