Cardiac mitral valve prolapse with insufficiency of closure, treatment methods include drug therapy and intra-aortic balloon counterpulsation. 1. Drug therapy: commonly used drugs include beta-blockers and antiplatelet drugs. Beta-blockers, such as propranolol and bisoprolol, are used to control arrhythmia and slow down the heart rate, etc. Antiplatelet drugs, such as aspirin and clopidogrel, are used to prevent thrombosis and avoid the occurrence of cerebrovascular accidents. Drugs such as captopril, etc., to relieve the symptoms of mitral valve closure insufficiency. The above medicines are used according to the doctor’s instructions. 2. Surgery: Surgical treatments include mitral valvuloplasty and mitral valve replacement. The purpose of mitral valvuloplasty is to repair the structure of the mitral valve and restore the normal function of the valve; mitral valve replacement replaces the structurally impaired mitral valve with a prosthetic valve, and is used for patients whose valves cannot be repaired. 3. Intra-aortic balloon counterpulsation: If hypotension occurs, surgical treatment should not be used; this method can reduce ventricular afterload. If the diagnosis of cardiac mitral valve prolapse with insufficient closure is confirmed, it is recommended to seek prompt medical treatment.