Frequent fluttering of the eyelids may be caused by physiological reasons, or may be caused by infections, central nervous system occupational lesions and other pathological reasons. 1. Physiological factors: temporary eyelid twitching may be due to eye fatigue, mental tension and other reasons, resulting in eyelid muscle fibers abnormal discharge and twitching, causing physiological eyelid twitching. 2. Pathological factors: Involuntary contraction and spasm of the orbicularis oculi muscle triggered by bacterial or viral infection. Clinical symptoms generally manifested as eyelid fluttering, involuntary closure, with the development of the disease can even lead to difficulty in opening the eyes. Occupational lesions in the nervous system, such as meningiomas, hemangiomas, neurofibromas, etc., can also lead to abnormal changes in the innervated eye muscles. Eyelid twitching may also occur due to dry eye, corneal foreign bodies, impingement and other eye irritations. If eyelid twitching occurs for a long period of time, it is recommended to go to the hospital to clarify the cause of the disease and standardize the treatment under the guidance of the doctor.