Diabetic foot is one of the most common complications of diabetes mellitus, refers to the lower limb infection, ulceration or even gangrene that occurs in diabetic patients on the basis of combined peripheral neuropathy and peripheral vascular disease, which requires amputation in serious cases and is the main cause of disability in diabetic patients. The initial symptoms of diabetic foot: First, the performance of diabetic foot neuropathy: mainly dullness or loss of sensation, numbness, muscle atrophy, weakened or absent knee tendon reflexes, the appearance of Charcot joint, foot deformities such as bowed feet, hammer toe, chicken claw toe, etc.. Nociceptive sensitivity, pins-and-needles, knife-like or burning pain in the extremities. Arterial pulsation is present. Second, it is the manifestation of diabetic foot vasculopathy: mainly arterial occlusion ischemia, cold feet, numbness, itchy skin, intermittent claudication. With the aggravation of the disease, resting pain will also appear, which is aggravated in the cold season or at night, and patients often sit on their knees and have difficulty sleeping at night, accompanied by dry skin, sparse sweat, deformed, thick, brittle toenails, and loss of luster; the dorsal foot artery and posterior tibial artery pulsation is weakened or disappeared. Thirdly, infection, ulceration and gangrene occur: localized skin congestion, swelling, blisters/blood blisters, ulcers, or pus cavities, sinus tracts, and wet or dry gangrene are seen. In severe cases, systemic symptoms also appear. When these abnormal manifestations are found, early further examination at a trauma repair specialist, together with control of the primary disease hyperglycemia, can effectively curb the further deterioration of the diabetic foot. The fundamental reason for the deterioration of diabetic foot is that high blood sugar persistently does not drop. Whether oral hypoglycemic drugs or insulin injections should try to control blood sugar, in addition to strict control of sugar intake in diet, and also appropriate exercise to promote the body’s ability to metabolize sugar.