Do I need to consolidate treatment after remission from chemotherapy for ovarian cancer recurrence?

  Patient: Description of condition (onset, main symptoms, hospital visited, etc.): Mother, now 60 years old, had a routine blood test in December 2004 CA125 index up to 600 or more, admitted to the hospital and diagnosed as right ovarian CA stage IIIC, December 2 surgery to remove all the uterus, bilateral adnexa. She was discharged from the hospital on December 19, 2004 and underwent five years of intensive chemotherapy followed by five years of herbal treatment. In the first half of 2010 to September, the CA125 routine blood test intermittently increased to more than 50 to 70 points, and on September 17, 2010 PET-CT diagnosed “thickening of the upper rectal wall” and increased FDG metabolism, considering malignant lesions and the possibility of metastases in the rectal wall. He was hospitalized on September 17, 2011, and was discharged from the hospital in April 2011 after four months of major chemotherapy (12 weekly chemotherapy sessions). At present, the condition is stable, and the second routine blood test CA125 is around 7 points for 3 months after discharge. The effect of chemotherapy is relatively obvious The doctor now offers two chemotherapy regimens: one is to focus on several courses of chemotherapy, i.e., my mother’s four consecutive chemotherapy 12 weekly treatments mentioned above, and the other is a major chemotherapy once, and then three months apart, and then chemotherapy, with intervals of chemotherapy during the renewal period. I don’t know which method of chemotherapy is ideal, or there are other good chemotherapy methods, please respect the doctor’s advice.  Tang Jie, Department of Gynecology, Cancer Hospital of Fudan University: The patient is in remission after chemotherapy for recurrent ovarian cancer and has stopped chemotherapy for 4 months. Currently, CA125 is at a low level (around 7), and if PET-CT can be repeated again to indicate reduced metastatic tumor activity in the rectal wall before chemotherapy, it would suggest complete remission. There is no definite conclusion on the consolidation treatment for ovarian cancer, besides, the patient has stopped chemotherapy for 4 months, so the time for consolidation treatment has been missed. The above comments are for your reference.