The incidence of intervertebral disc infections is increasing clinically, so here are a few questions to help you recognize and understand intervertebral disc infections The intervertebral disc tissue is the largest blood-supply-free tissue in the body and is therefore weak against pathogenic factors such as bacteria, especially in individuals with poor nutritional status who are more prone to intervertebral infection. When an infection occurs in the intervertebral space, the local inflammatory lesion can irritate the surrounding tissues causing unbearable pain and fever when the inflammation is active. Patients often seek medical attention for these two reasons, and fever may sometimes be reduced to normal with general anti-inflammatory treatment, but the condition often recurs. 2. What are the causes of intervertebral space infection? There are two main categories of intervertebral space infections observed clinically, one is the infection that occurs after disc surgery, which used to be the main cause of intervertebral space infections and involves the treatment of the first surgery and the original cause, which is more difficult to deal with, and the prognosis is sometimes difficult to be satisfied. Another category is hematogenous, where the primary lesion is mostly from the skin, mucosa or urinary tract. It is mostly seen in the elderly population, with poor nutritional status and poor self-reliance. Recently, there has been a gradual increase in this group of patients. 3.What are the treatment options for intervertebral space infection? What is the effectiveness of conservative treatment? There are two main types of treatment: conservative treatment, which is called anti-inflammatory (antibiotic) treatment, and surgical treatment + post-operative antibiotic treatment. Due to the poor blood supply, it is often difficult to form an ideal drug concentration or drug duration at the lesion by oral or intravenous antibiotics, thus failing to destroy the bacteria at the lesion more completely. 4.What are the advantages of surgical treatment of intervertebral space infection compared to conservative treatment? Through surgery, it can directly reach the intervertebral space with poor blood supply to remove the lesion more thoroughly and create good conditions for antibiotic treatment; it can help to make a clear diagnosis and culture specific bacteria from the lesion tissue, which can help doctors to draw up a more accurate treatment plan; 5, how is minimally invasive surgery for intervertebral infection performed? It usually requires percutaneous internal fixation from the back of the lower back, followed by a small incision about 5 cm long on the outside of the lower abdomen to access the lesion, remove the necrotic material, and continue local irrigation with antibiotics. 6.What do I need to pay attention to after the intervertebral space surgery? After patients can eat, they need to pay attention to supplemental nutrition. Generally, they need to rest in bed for 3-4 weeks after the operation, after which they need to move on the ground with the assistance of a rigid support.