The main difference between nephritis and UTI is the cause, symptoms and treatment. 1. Causes: Nephritis usually refers to glomerulonephritis, which is an immune system disease, mainly due to a variety of reasons caused by the body’s immune imbalance and the emergence of a disease; and urethritis is a kind of infectious disease, usually because of exogenous pathogenic microorganisms invade the urinary system caused by a kind of inflammation. 2. Symptoms: Nephritis patients mainly manifested as hematuria, proteinuria, edema, hypertension, etc., while patients with urethritis mainly manifested as frequent urination, urinary urgency, urinary pain, as well as lumbar discomfort, elevated body temperature and other symptoms. 3. Treatment: patients with nephritis can usually be treated with glucocorticosteroids such as prednisone and immunosuppressants such as cyclophosphamide under the guidance of a doctor; while patients with urethritis are usually treated with antibiotics such as levofloxacin and cefuroxime under the guidance of a doctor. Patients with nephritis and urethritis are advised to go to regular hospitals in time and receive standardized treatment under the guidance of doctors.