The symptoms of generalized joint pain with fever may be related to a variety of factors, including acute septic arthritis, brucellosis arthritis, rheumatoid arthritis, rheumatoid arthritis, etc. Patients are advised to seek medical attention promptly after the appearance of the symptoms to clarify the specific causes and then treat accordingly. 1. The disease starts rapidly and fever is obvious, the joint cavity may have purulent exudate, resulting in general joint pain with fever. The disease can be treated with broad-spectrum antibiotics, such as ceftriaxone sodium for injection, cefoperazone sodium for injection, levofloxacin hydrochloride capsules, etc. If the effect is not good, it is necessary to treat through joint drainage; 2, brucellosis arthritis: is a disease caused by brucellosis infection, characterized by long-term fever, joint pain, can lead to generalized joint pain with fever, and joint pain occurs more in It is characterized by prolonged fever and arthralgia, which can cause generalized joint pain with fever. The rheumatoid arthritis is an autoimmune disease that causes mild fever and joint lesions in the small joints of the hands and feet, accompanied by pain and swelling, resulting in generalized joint pain with fever. It can be treated with antipyretic and analgesic drugs, such as ibuprofen extended-release capsules, and methotrexate tablets for anti-rheumatic treatment, and with physical therapy; 4, rheumatoid arthritis: before the onset of the disease, there is often a history of hemolytic streptococcal infections, such as pharyngitis, tonsillitis, etc., often accompanied by other features of rheumatic fever, such as subcutaneous nodules, annular erythema, etc. Most of them start with acute fever and arthralgia, and the affected joints are mostly lacquer, shoulder, ankle, elbow, wrist and other large joints. Most of the joints involved are large joints such as lac, shoulder, ankle, elbow, wrist, etc. The pain is wandering and causes generalized joint pain with fever. In addition, the symptoms of generalized joint pain with fever may also be related to common cold, lupus erythematosus, or advanced bony metastasis of malignant tumor. Patients are suggested to seek medical treatment in time, improve blood routine and other related examinations, and carry out targeted treatment to avoid delaying the treatment time.