Zinc deficiency in babies can be supplemented in vitro, including dietary and medication supplements, and etiological treatments are also needed for diseases such as pediatric diarrhea. The body itself can not synthesize zinc, zinc deficiency prevention and treatment mainly rely on in vitro. In vitro supplementation includes the consumption of zinc-containing foods and the use of medications. For children over 6 months of age, zinc-containing complementary foods can be added, such as animal foods rich in zinc, including meat, poultry, and fish. Medications, such as zinc gluconate and calcium oral solution, can also be prescribed. It is important to note that in addition to supplemental zinc, for some diseases resulting in zinc deficiency, it is also necessary to address the cause of the treatment, such as symptomatic diarrhea resulting in the need to apply probiotics (e.g., Bacillus subtilis bacillus granules), montelukast and other medications to alleviate the symptoms of diarrhea, thereby reducing the loss of zinc. When a child has a zinc deficiency, he or she should go to a regular hospital and take supplements under the guidance of a doctor.