Considering the reason for the current outbreak, the nucleic acid test may refer to the neocoronavirus nucleic acid test, and eating durian does not usually affect the neocoronavirus nucleic acid test. Currently, neocoronavirus nucleic acid test is mainly performed by collecting pharyngeal secretions through throat swabs, and determining whether there is neocoronavirus infection by detecting the presence of neocoronavirus nucleic acid in the secretion samples. Eating durian does not affect the nucleic acid of the virus and therefore will not affect the nucleic acid test result. However, if you do not rinse your mouth after eating durian and there is durian residue in your throat, it may cause medical personnel to take samples without accurately picking up the effective secretion, which is not conducive to sampling. It is recommended to rinse the mouth in time after eating durian, and also pay attention to keep a proper distance for protection when doing nucleic acid test.