Urine protein 2+ suggests a moderate amount of protein in the urine, most commonly due to kidney disease, and is divided into transient proteinuria, upright proteinuria, and persistent proteinuria. Transient proteinuria and upright proteinuria are usually not serious, but persistent proteinuria is mostly seen in kidney disease, which is usually more serious and requires treatment. 1. Transient proteinuria: transient proteinuria often appears after strenuous exercise or fever, which is manifested as positive urine protein, but after rest and treatment of fever, the urine protein is negative on recheck, and the kidneys do not have disease conditions, and transient proteinuria can be left untreated. 2. Upright proteinuria: upright proteinuria is mostly seen in adolescents, especially those with lean and tall body types, and proteinuria occurs when the body is upright for a long time, and can disappear after lying down, mainly due to pressure on the renal veins after standing, which is usually not serious; 3. Persistent proteinuria: persistent proteinuria is mostly seen in kidney diseases, such as primary glomerulonephritis and secondary nephritis, such as systemic lupus erythematosus nephritis, allergic Purpura nephritis, as well as urinary tract obstruction, renal tubular injury, hypertensive nephropathy, diabetic nephropathy, etc. In addition to proteinuria, these diseases are often accompanied by hematuria, edema and other uncomfortable symptoms, which are more serious and require timely treatment. Excess urine protein in urine provides an important reference for the early detection of kidney damage and various diseases, and plays a certain clinical significance for the detection of various glomerular diseases.