Generic name is amlodipine benzenesulfonate, and Irbesartan are two different types of antihypertensive drugs, there is no difference between good and bad. According to the patient’s hypertension type and characteristics, as well as the accompanying diseases and complications, choose the one that is suitable and has less adverse effects, which is called individualized treatment. 1. Amlodipine benzenesulfonate: it belongs to dihydropyridine calcium antagonist, which mainly reduces blood pressure by inhibiting myocardial contractility and dilating blood vessels, and it also has certain effect on variant angina pectoris caused by coronary artery spasm; it can reduce albuminuria to a certain extent, and it can protect renal function, which is suitable for hypertensive patients accompanied by left ventricular hypertrophy and renal insufficiency. Its main adverse reactions include flushing, panic, peripheral edema, abdominal pain, nausea, dizziness, headache, drowsiness, fatigue and so on. Allergic to drug components, patients with severe hypotension, patients with severe aortic stenosis is prohibited. 2. Irbesartan: belongs to angiotensin 2 receptor antagonist, can treat hypertension. The main adverse effects of this product include dizziness, flushing, musculoskeletal injury, nausea, etc. Upright hypotension, dyspepsia and diarrhea may also occur. This product for severe congestive heart failure, severe renal insufficiency, bilateral renal artery stenosis patients can cause acute renal failure, therefore, these patients should be used with caution or even prohibited. If you need to use the above drugs for hypertension, you should choose and use them in a standardized way under the guidance of a specialist to avoid adverse consequences.