Most patients with multisystem atrophy are bedridden before they die, resulting in multiple organ failure, poor nutritional status, and often die from infectious diseases, as follows: 1. due to bedridden, nasal feeding may appear as crash pneumonia, aspiration pneumonia, as well as bedsores, infections, urinary tract infections, etc.; 2. patients show symptoms such as fever, abdominal pain, but also due to poor nutritional status, renal failure after the performance of anuria or oliguria, poor cardiac function resulting in swelling of the limbs, and electrolyte disorders to form drowsiness or coma, etc. The symptoms of multisystem patients with atrophy before they die are related to the damaged internal organs.