Medications used to treat ulcerative colitis include aminosalicylic acid, glucocorticoids, immunosuppressants, and biologics, as well as surgery in severe cases. There is no such thing as the most effective medication, only the most appropriate medication for the patient. 1. Aminosalicylic acid: such as salicylazosulfapyridine, mesalazine, etc., mainly used for mild to moderate colitis treatment, can effectively alleviate the symptoms caused by the colon. 2. Glucocorticoids: such as prednisone, prednisolone, etc., for the acute stage of ulcerative colitis has a significant therapeutic effect. 3. Immunosuppressants: commonly used azathioprine and mercaptopurine, mostly used in aminosalicylic acid maintenance therapy is ineffective, recurrent symptoms and hormone dependence of the maintenance therapy. 4. Biological agents: such as infliximab, can be used under the guidance of the doctor when the above drugs are not good treatment. If the patient is combined with intestinal obstruction, peritonitis and other accompanying symptoms, on the basis of drug treatment, surgical treatment may also be required. Because patients have individual differences, and the specific condition of the patient is not the same, it is recommended that patients with colitis timely to the hospital, according to the patient’s specific situation to take the most appropriate treatment program to help patients as soon as possible to cure. Drugs need to be used under the guidance of a professional physician, do not self-medicate.