There is no evidence that lovastatin can reduce creatinine and urinary protein. Lovastatin belongs to the class of statins, and some studies have shown that statins have the potential to improve renal function or delay the deterioration of renal function by altering renal hemodynamics or inhibiting inflammatory responses, etc. However, there is no clear evidence for the time being that lovastatin has the ability to lower creatinine and urinary protein. According to the instructions for use of the drug, lovastatin is indicated for use in the treatment of hypercholesterolemia and mixed hyperlipidemia, common adverse reactions include gastrointestinal discomfort, diarrhea, flatulence, headache, rash, elevated liver enzymes, etc., and is contraindicated in people who are allergic to the drug, have active liver disease or unexplained persistent elevation of blood aminotransferase, and should be used with caution in people who are allergic to other HMG-CoA reductase inhibitors. According to the instructions of the drug, lovastatin has no effect on lowering creatinine and urinary protein, and it is recommended to follow the doctor’s instructions.