Gastrointestinal mesenchymal tumors are potentially malignant tumors, and therefore the severity of gastrointestinal mesenchymal tumors should be based on the exact size as well as the degree of malignancy. Gastrointestinal mesenchymal tumor is a tumor of mesenchymal origin of the gastrointestinal tract, which can be either benign or malignant in its biological behavior. Gastrointestinal mesenchymal tumors are generally considered benign when they are less than 2 cm in diameter. Early symptoms of gastrointestinal mesenchymal tumors are not obvious and treatment is often easily delayed. Therefore, if gastrointestinal mesenchymal tumors are detected early, and the tumor diameter is small and does not show obvious clinical symptoms, the prognosis is generally better after aggressive surgical resection. The later the gastrointestinal mesenchymal tumor is detected and the larger its size, the higher its malignancy may be. If the gastrointestinal mesenchymal tumor is not detected in time, the degree of malignancy increases, and even spread and metastasis occurs, it is more serious, and then it is recommended to carry out surgical resection as appropriate after treatment with Imatinib.