How does polycystic ovaries affect IVF?

The advantage of IVF treatment for polycystic patients compared to other infertile women is that they have a good ovarian reserve and can obtain a large number of mature eggs for fertilization after ovulation promotion. This is an advantage, but it is also a disadvantage. When too many follicles develop after ovulation promotion, the woman’s body becomes more estrogenic and is prone to a medical condition called ovarian hyperstimulation syndrome (OHSS). OHSS does not occur in the natural state, but only after ovulation promotion treatment, because the excessive estrogen changes the permeability of blood vessels, and many components of blood vessels enter the lumen, forming pleural fluid, ascites, etc.; at the same time, because of the concentration of blood in blood vessels, blood clots are easily formed, which may be life-threatening in serious cases. In order to reduce the occurrence of OHSS, the fertility doctors have been doing everything possible and have gained a lot of experience. For example, the use of appropriate ovulation protocols to control the number of developing follicles, early night injections, small follicle puncture, use of GnRHa trigger instead of HCG, elimination of fresh embryo transfer, etc. In this safety-first atmosphere, patients can get the right number of mature eggs and, at the same time, the occurrence of OHSS, especially moderate to severe OHSS, is greatly reduced. In addition, for women with polycystic ovary syndrome, in addition to polycystic ovarian-like changes, there are also endocrine abnormalities and metabolic abnormalities which can also affect the outcome of IVF treatment. In clinical treatment, we have found that although women with PCOS get many eggs, there are often few high-quality embryos. Summing up our experience, after improving the abnormal endocrine status and metabolic status of our patients, the rate of superior embryos is greatly improved and the clinical pregnancy rate of infertile women with PCOS is greatly improved. In summary, the goal for women with polycystic women in IVF treatment should be to have the right number of eggs, and this is up to the fertility doctor to worry about for you. Before entering the IVF treatment cycle, one should have the patience to adjust the endocrine and metabolic status. The most commonly heard phrase is to abstain from sugar, reduce oil, exercise and lose weight. If you can really do this, you are already halfway to the threshold of a successful pregnancy.