Pain in the crook of the leg, also known as knee pain, requires different treatment depending on the condition. If the pain is caused by soft tissue injury around the knee joint, you should use topical creams or sprays to relieve pain and swelling after the injury, such as blood circulation and pain relief cream or Yunnan Baiyao aerosol, etc. Oral medications such as blood circulation and blood circulation capsules, Shenyang Red Medicine capsules and acupuncture are effective. If the pain is caused by damage to the cartilage in the joint, oral medication such as Panax notoginseng tablets, Mai Zhi Ling tablets and Vigorix should be taken; external treatment with anti-stasis and pain relief cream should be applied to the thighs and calves above and below the knee joint.