With the spread of knowledge about eugenics, most young people are aware that the health of their offspring is influenced by various conditions. Potential illnesses, undetected genetic diseases from grandparents, certain foods, drugs and bad habits such as smoking and alcohol consumption may affect the health of the fetus after pregnancy. Therefore, when there is a plan to “make a man” must be prepared in advance, to understand whether they are suitable for pregnancy, what should be done, what must be avoided; after pregnancy adhere to the standard pregnancy test, timely detection of fetal abnormalities, step by step, step by step, to avoid the occurrence of tragedy. Marriage Premarital checkups are responsible for the health of new family members in the future. Especially in the past few years of the abolition of marriage examination, birth defects children increased significantly, and soon aroused people’s awareness, and now the rate of marriage examination in Shaoguan area has gradually climbed. Premarital physical examination has the following significance: 1, if both sides of the body if there are diseases or defects, can be found in time through premarital physical examination, timely treatment to ensure a happy and fulfilling life after marriage. 2, certain congenital abnormalities of the genitalia can be found and corrected before marriage, so as to avoid unnecessary anxiety and sexual dysfunction after marriage, for example: hymen hypertrophy or narrow, abnormal development of the uterus, etc. 3, certain diseases that can affect the offspring can be detected or clarified before marriage, after marriage to pay attention to contraception, so as not to pass on to the next generation. Pregnancy Some young couples think that they have always been in good health, and there is no cold or fever before pregnancy, so they can get pregnant naturally and do not need to do pre-conception tests. This is not the case. Pre-conception check-ups are not the same thing as medical check-ups, the purpose of which is to prevent your own diseases, but for pregnant women, pre-conception consultation and check-ups are the key to having a good birth. Many women of childbearing age have some reproductive system infections, and the dangers of these infections are well known to the majority of women. However, not much is known about infections with Toxoplasma gondii, rubella virus, cytomegalovirus, herpes simplex virus and other specific viruses, which have no obvious symptoms and are not easily detected by preconception tests. These viruses can have a significant impact on normal conception, and in some severe cases can even lead to fetal malformations. In addition, preconception tests can help mothers to eliminate common risk factors for miscarriage and fetal malformations. Such as genetic factors, reproductive organ malformations or diseases, infections, endocrine factors, immune factors, etc. It is important to have a healthy baby as safely as possible. Especially for “advanced” mothers who become pregnant after the age of 35, it is important to do preconception checkups in time and plan the pregnancy carefully. What tests should be done before pregnancy? First of all, virological tests for intrauterine infections: cytomegalovirus, toxoplasmosis, rubella virus, herpes virus, etc. are needed to determine the infection status. If a woman is found to be antibody positive before pregnancy, it is best for the health of the next generation to undergo treatment and regular monitoring under the guidance of a doctor until the antibodies turn negative before considering pregnancy. Secondly, it is best for women to have a gynecological examination before pregnancy. Some pathogenic microorganisms in the reproductive tract, such as gonococcus, syphilis spirochetes and Chlamydia trachomatis, can also cause in utero infection in the fetus and affect the normal development of the fetus. If there is an infection, conception should be delayed and treated first. In addition, women of childbearing age should also have an ultrasound examination before conception to understand the basic condition of the uterus and adnexa. Maternity checkup The health of the child will be directly related to the happiness and happiness of the family. Therefore, it is very important for the stability and happiness of families to find relevant high-risk factors through prenatal medical checkups and eugenic guidance, and to make preconception interventions for factors affecting eugenics and fertility to reduce the occurrence of miscarriage, fetal malformation and pregnancy complications. Obstetrical and gynecological examination programs must be selected by professional obstetricians and gynecologists according to the specific situation of the subject, and reasonable examination programs, comprehensive, objective and scientific analysis of the subject’s medical records and examination results, and timely treatment and guidance for the detected diseases. Here I will mention only the most important tests: NT test and early Down’s screening at 11-13+6 weeks of pregnancy, which can screen out about 90% of congenitally stupid fetuses; ultrasound screening for large malformations (called Class III screening by doctors) at 22-24 weeks of pregnancy to exclude most structural malformations of the fetus. Exceptionally high-risk pregnant women need to be screened more intensively both before and during pregnancy, and also need to undergo prenatal diagnosis (also known as intrauterine diagnosis and pre-birth diagnosis). Pregnant women with one of the following conditions should undergo prenatal diagnosis: ① senior pregnant women aged ≥35 years; ② history of habitual miscarriage and stillbirth; ③ history of exposure to fetal teratogenic factors in early pregnancy; ④ excessive amniotic fluid; ⑤ history of delivery of chromosomally abnormal children; ⑥ one of the couple is chromosomally balanced translocation or chimeric; ⑦ history of delivery of children with neural tube abnormality or limb abnormality; ⑧ ultrasound fetal structural abnormalities; ⑨ one of the couple is One of the couples is a carrier of X-linked genetic disorder, or has a family history of X-linked genetic disorder. For diseases with abnormal fetal chromosome number or structure, fetal cells of fetal origin are obtained by invasive diagnostic methods (chorionic villus sampling, amniocentesis and percutaneous umbilical vascular puncture) during pregnancy, and karyotype testing is performed to detect and confirm the diagnosis, enabling early termination of pregnancy before delivery. We can also detect many genetic disorders such as thalassemia major and other serious health risks to the baby through prenatal diagnosis. Marriage test, preconception test and maternity test are indispensable to ensure a healthy baby.