If a woman develops facial swelling in the second trimester of pregnancy, it is most likely due to edema caused by changes in hormone levels in the body as a result of pregnancy. If it is not accompanied by abnormalities in blood pressure or protein in the urine, there is no need for special attention, and attention should be paid to rest. The edema will gradually disappear and return to normal after normal delivery. If there is edema of the face, along with edema of the legs, pleural effusion or abdominal effusion, and if it is accompanied by high blood pressure or abnormal protein in the urine, it means that hypertensive disorders of pregnancy may be present, which is a complication of pregnancy in women. Hypertensive disorders of pregnancy tend to occur after 20 weeks of gestation and have a lot to do with the patient’s constitution. Treatment requires symptomatic treatment, lowering blood pressure, as well as antispasmodic and sedative therapy, supplementation of blood proteins. In severe cases, diuretics can be applied appropriately, but when applying diuretics, it is important to be aware of the possibility of affecting the fetus, as it can cause electrolyte disorders in the blood. In itself, diuretics are a relatively unsafe drug in the state of pregnancy, so when applying them, the effect on the pregnant woman and the fetus should be carefully assessed.