Both aortic and coronary atherosclerosis are dangerous, but the severity varies from patient to patient depending on their physical condition. The main pathological manifestations of atherosclerosis are the thickening and hardening of the arterial wall, loss of elasticity, and narrowing of the lumen. The lesions begin in the lining of the arteries and are accompanied by a variety of lesions both before and afterward. 1. Aortic arteriosclerosis; aortic arteriosclerosis is more common and its severity varies from person to person. Since it is a relatively thick arterial vessel, it has less impact on the blood supply of the whole body when the lesion occurs, so the result of aortic atherosclerosis is relatively mild. With aortic atherosclerosis, there is an increased risk of aortic coarctation, which is a critical disease that is dangerous and requires prompt treatment. 2. Coronary atherosclerosis: The left anterior descending branch of the coronary artery is a favorable site for coronary atherosclerosis. Coronary artery is the main blood vessel of the heart, if its hardening and narrowing, it will lead to ischemia of the heart, pre-symptoms are mainly angina pectoris after activity, rest and take drugs such as nitroglycerin can relieve, stenosis is more serious, myocardial ischemia is severe, it will lead to large infarction. The degree of inflammation of coronary atherosclerosis is mainly determined by the degree of its stenosis, most patients can be controlled by drugs. When it is greater than 75% and medication is ineffective, prompt surgical or interventional treatment is required. Atherosclerosis is a dangerous condition and should be treated and prevented under the guidance of a doctor if symptoms occur.