Aminophylline has more side effects, related to the dose, the more serious ones being the possibility of arrhythmia, drop in blood pressure and even death. The most serious side effects have the potential to cause cardiac arrhythmia, drop in blood pressure, chest tightness, agitation, convulsions and even sudden death. The systemic side effects of aminophylline are mainly manifested in the excitatory effects on the central nervous system and the heart, such as tremor, agitation, headache, dizziness, anxiety, palpitations, etc., which are mostly seen when aminophylline is applied intravenously and the infusion time is too fast. Therefore, it is recommended that blood levels be checked when aminophylline is administered intravenously. Aminophylline oral side effects are mainly in the digestive system, such as nausea, vomiting, abdominal pain, diarrhea, etc., usually can be tolerated after taking the drug for 2~3 days. Aminophylline use must pay attention to: allergy to theophylline, blood pressure below 90/60mmHg, shock or in shock, tachycardia, arrhythmia, acute myocardial infarction, hyperthyroidism, gastric ulcer, epilepsy patients belong to the contraindications to the use of aminophylline, can not be used. The use of aminophylline should be strictly in accordance with medical advice to avoid serious adverse reactions.