As we all know, the main way of transmission of HPV virus is through sexual intercourse, and for HPV vaccination, many people prefer the nine-valent HPV vaccine because it provides the most comprehensive protection against 90% of cervical cancer. In addition, HPV vaccination is best done before the first sexual intercourse. The vaccination is recommended to be done before the first sexual intercourse, not before the first sexual intercourse. If you are a woman who has already had sex, you can also inject the nine-valent vaccine, which can also play a very good preventive effect. The nine-valent vaccine mainly plays a preventive role against nine types of HPV virus, focusing on high-risk HPV virus types 16, 18, 31, 33, 45, 52, 58, and low-risk HPV virus types 6 and 11. Therefore, HPV vaccination can prevent the initial infection of certain viruses, as well as prevent the occurrence of deeper lesions in patients who are already infected, and prevent recurrence of cervical lesions that have already been treated. People who are suitable for the nine-valent vaccine in China are 16-26 years old and need to complete three doses within six months, where the interval between vaccinations is 0-2-6 months. So not being a virgin is not a major contraindication to receiving the nine-valent vaccine, and it is recommended that women who are age-eligible get the nine-valent vaccine! However, women who have a sexual life need to pay attention to 2 points before the injection: 1. Vaccinators need to be regularly checked for HPV virus before and after the injection to observe whether there is infection. 2. Women who cannot exclude pregnancy must undergo pregnancy-related screening, because patients cannot inject the vaccine after pregnancy is found, or in the process of injection, without good contraception, have found to be pregnant, the injections should be stopped immediately and the remaining injections should be completed after delivery. References: [1] Hu Guiqiong. Is the cervical cancer vaccine important? Should we get it or not? [J]. Health Care Guide.2019,43:63 [2] Li Zhengxing,Sheng Yonghong. A survey of nine-valent human papillomavirus vaccination among female students in a higher education institution in Yunnan [J]. Journal of Practical Medical Technology. 2021,28(7): 847-850