Duodenal perforation, gastric perforation, considered to be related to duodenal ulcer, gastric ulcer, is a serious complication belonging to the ulcer, about 10% of the patients have a history of ulcer, sudden acute perforation. Patients with duodenal ulcer, gastric ulcer perforation mainly manifested as sudden severe epigastric pain, such as knife-like pain, persistent or paroxysmal aggravation, accompanied by nausea and vomiting, fever and other typical manifestations. With the further aggravation of the condition, it can cause cold sweat, pallor, and elevated body temperature. In severe cases, it can be accompanied by a drop in blood pressure, causing complications such as purulent peritonitis and shock. To summarize, duodenal and gastric perforation is a kind of acute abdomen, and the condition is usually more serious. It is recommended to go to the gastroenterology department of the hospital in time and undergo surgery if necessary to avoid serious harm.