Urine glucose 4+ has no direct relationship with the amount of blood sugar, urine glucose 4+ may be caused by poor blood sugar control, medication, kidney disease and so on. 1. Poor blood sugar control: If you suffer from diabetes, checking the urine glucose 4 +, indicating that the blood sugar control is not good enough. If this is the case, you should check the fasting blood glucose, 2 hours after meals blood glucose and glycated hemoglobin to determine what level of blood glucose. According to the results of the examination to adjust the sugar-lowering program. 2. Drugs: Diabetic patients taking sodium-glucose co-transporter protein 2 (SGLT-2) inhibitors, such as dagliflozin and empagliflozin, will result in a decrease in blood glucose and a positive urinary glucose, or even urinary glucose 4+. 3. Kidney disease: If the patient does not have diabetes per se and only has 4+ urine glucose, he/she should be further checked for blood glucose and glycated hemoglobin to understand the blood glucose situation as well as the blood glucose level in the last 2-3 months. If there is no abnormality in the examination and the urine sugar is still high in the retest, it means that there may be diseases in other organs such as kidneys, which need further examination and treatment under the guidance of the doctor. If the test found that the urine sugar 4 +, must pay attention to, timely to the hospital to avoid serious consequences.