The following diseases can lead to elevated CA-125 values: 1. diffuse pelvic inflammatory disease 2. endometriosis, chocolate cysts 3. inflammatory pelvic masses 4. fluid and pus accumulation in the fallopian tubes 5. pelvic and abdominal tuberculosis 6. ovarian cysts, uterine fibroids 7. destruction of epithelial cells in the body cavity due to any cause: chronic hepatitis, chronic pancreatitis, etc. Elevated CA-125 due to the above conditions is mostly mild to moderate Most of the elevations are below 200 U/ml. Although elevated CA-125 does not exactly mean ovarian cancer, it is very closely related to ovarian cancer, and it is the main marker of epithelial ovarian cancer (especially plasma adenocarcinoma), with 35 U/ml as the threshold value, the diagnostic sensitivity can be more than 90%. diagnosis and early treatment.