The common causes of itching all over the body after two chemotherapy treatments for esophageal cancer are as follows: 1. Chemotherapeutic drugs as well as auxiliary drugs for chemotherapy may lead to itching of skin, which belongs to allergic reaction, and clinically it is more common that capecitabine and paclitaxel drugs lead to itching of skin. Patients often use drugs, itching is more serious and can not be relieved, you can use anti-allergy drugs. If necessary, need to adjust the treatment program under the guidance of the doctor 2. If it is an elderly patient, itself will also appear dry skin leading to itchy skin, after chemotherapy will promote its more itchy. Patients use skin lotion, mainly to avoid dry skin. If it is winter, try to avoid bathing every day, you can reduce the number of baths. The itching will be more serious after the sebum is removed from the skin when bathing in hot water. 3. If the patient himself has some skin diseases, chemotherapy may also lead to aggravation or recurrence of skin diseases. It is recommended that the patient go to a regular hospital to clarify the cause of the disease and receive appropriate treatment. Avoid scratching as much as possible, so as not to cause skin breakage and aggravate the risk of infection.