There are many diseases that cause a tingling sensation in the lungs when smoking, including chest diseases such as rib fracture, cardiovascular diseases such as angina pectoris, respiratory diseases such as pleurisy, and mediastinal diseases such as mediastinitis. The lungs themselves are not innervated by pain nerves and do not feel pain. If a tingling sensation in the lungs occurs when smoking, it is generally considered to be chest pain. Diseases that commonly cause chest pain are: 1. Chest diseases: rib fracture, epidemic chest pain, myositis, non-suppurative costochondritis, intercostal neuritis, acute leukemia, multiple myeloma and so on. 2. Cardiovascular diseases: acute myocardial infarction, coronary angina pectoris, acute pericarditis, pulmonary hypertension, mitral or aortic valve lesions and cardiac neurosis, etc. 3. Respiratory diseases: pneumonia, spontaneous pneumothorax, acute tracheo-bronchitis, pleural tumor, lung cancer, etc. 4. Others: subphrenic abscess, mediastinal tumor, liver abscess, splenic infarction, esophageal cancer, etc. There may be other reasons for the tingling sensation in the lungs from smoking, so it is recommended to go to the hospital in time, improve the examination to clarify the cause of the disease, and then give targeted treatment or therapy.