Headache after fever reduction may be neurological and infectious and other reasons, to clarify the cause of the disease to choose specific treatment, such as analgesic treatment, anti-infective treatment and so on. 1. Neurological headache: during the fever, the body’s immune system is mobilized, poor rest or mental stress, forehead, eyebrow ridge, side headache, dull pain or tightness. You can take oral ibuprofen suspension to relieve pain and vitamin B12 to nourish the nerves as prescribed by the doctor. 2. Infectious headache: fever is usually infected with viruses, bacteria, etc. If the treatment is not timely or improperly handled, intracranial infection occurs, headache, nausea, vomiting and other symptoms. It is necessary to carry out germ culture or antigen test to clarify which pathogen is infected and then choose drugs, such as cefuroxime and ribavirin. Headache after fever reduction can also be caused by temporary insufficient blood supply to the brain or lack of oxygen, if it continues to be unrelieved, we should go to the hospital in time for examination, to clarify the cause of the disease, and active treatment. The use of drugs must follow the doctor’s instructions, not blindly use their own drugs, so as not to cause adverse consequences.