The cycle of liver self-repair of elevated alpha-fetoprotein is usually 3 to 5 months. It is a normal reaction that alpha-fetoprotein will be elevated during liver self-repair. It is of value in the diagnosis, efficacy, detection of recurrence and prognosis of tumors. When liver cells are damaged liver cells will resume regeneration, and then the response of alpha-fetoprotein will be elevated, but usually the magnitude of elevation is relatively small, and when liver inflammation improves the alpha-fetoprotein will return to the normal level. If the alpha-fetoprotein remains elevated after the liver function has returned to normal, it is recommended that further investigations be performed according to the patient’s clinical manifestations and in accordance with the doctor’s instructions. When liver cells are damaged and regenerate, genes related to alpha-fetoprotein will be reactivated, causing alpha-fetoprotein to be re-synthesized and released into the bloodstream, leading to an increase in alpha-fetoprotein.