If the urinary tract infection is significantly painful, it is recommended to go to the hospital for symptomatic treatment: 1. According to the results of urine culture and drug sensitivity test, it is necessary to choose sensitive antibiotics for treatment, such as oral levofloxacin hydrochloride capsules or cefixime capsules. After the infection is controlled, the pain can be gradually reduced or relieved. 2, oral symptomatic analgesic drugs, for the acute pain period, give oral diclofenac sodium capsules or fenpropidin capsules and other drugs symptomatic analgesic treatment, temporary relief of the patient’s pain. 3, oral sodium bicarbonate tablets of alkalinization of urine, reduce the mucosal irritation caused by urinary tract infection, so as to moderately reduce the patient’s pain. 4, if necessary, perform suprapubic cystocentesis drainage to reduce pain, such as acute inflammation exists in patients with urethral erosion, urine irritates the erosion trauma, which can then produce acute pain. After the suprapubic cystocentesis fistula for urinary diversion, urine does not stimulate the local mucous membrane of the erosion, then the pain can be reduced or disappeared, wait for the complete healing of inflammation, and then resume normal urination.