There is no absolute contraindication between interferon and Vitamin A. Interferon can be used at the same time as Vitamin A. However, if it is used externally at the same time, it is recommended to be applied separately, and attention should be paid to the adverse reactions and contraindications in the use of the drug. Interferon is prohibited to be paired with cimetidine, warfarin, theophylline, diazepam and other drugs; Vitamin A acid is prohibited to be paired with vitamin A, tetracycline and other drugs. There is no contraindication between the two, can be used at the same time; but if the simultaneous topical use of interferon and Vitamin A gel or cream, in order to avoid excessive application of drugs, it is recommended to use separately. Interferon is commonly used in the treatment of viral hepatitis or warts virus infectious diseases, renal cancer or laryngeal papilloma and other malignant tumors, in the use of fever, arthralgia, thrombocytopenia, neurological dysfunction adverse reactions, it is recommended to go to the hospital in a timely manner. For drug allergy, serious cardiac, liver and renal insufficiency and other conditions prohibit the use of drugs. Retinoic acid is commonly used in the treatment of acne, psoriasis, acute promyelocytic leukemia and other diseases, in the use of conjunctivitis, hyperlipidemia, hepatic dysfunction and other adverse reactions, it is recommended to go to the hospital in time. For pregnant women, liver and kidney severe functional insufficiency and other conditions prohibit the use of drugs. Interferon and Vitamin A need to be used under the guidance of a clinician, do not use the drug without authorization.