The early symptoms of female acromegaly are mainly characterized by skin and mucous membrane proliferations. Female acromegaly is mostly found in the labia majora and minora, vaginal opening, vagina, cervix, clitoris, and perianal skin and mucous membranes, and a few patients will be in parts other than the anogenital area, such as the armpits, breasts, and oral cavity. The patient’s lesions begin as a single or multiple scattered light red pimples, the texture is relatively soft, with time gradually increase in size, papillary, cauliflower, cockle and grass-like, warts are white, pink or gray. Most patients do not have obvious self-conscious symptoms, a few patients will have burning pain, itching, foreign body sensation or discomfort of sexual intercourse. It is recommended that patients who have high-risk behaviors promptly go to the hospital, with the help of the doctor to clarify the diagnosis, so as not to delay the condition.