The cause and pathogenesis of psoriasis are not well understood at present. It is generally believed to be related to various factors such as genetics, infection, psychiatric, endocrine and immune factors, and is a multi-gene genetic disease with the interaction of multiple factors. Although great progress has been made in basic research on the biochemistry, immunity, genetics and molecular biology of psoriasis. However, two unique clinical features of psoriasis have been underappreciated, namely, the first onset of psoriasis and the exacerbation of psoriatic lesions are often associated with psychological stress and trauma. Moreover, since there is no cure for this disease, its recurrent and prolonged course, the economic burden of long-term treatment and the clinical features of damaged skin and unbearable itching have further endangered the physical and mental health of patients. Paying attention to the psychological factors of psoriasis patients and attaching importance to the psychological intervention treatment of psoriasis patients are important for improving symptoms, delaying recurrence and improving patients’ quality of life. Among them, health education and psychological intervention treatment is a means with both economic and social benefits, and has a broad application prospect.