Duodenal gastric ulcer does not exist the best drugs, need to be treated symptomatically according to the specific condition and symptoms, as follows: First, drugs to protect the gastric mucosa, can form a protective layer on the surface of the gastric mucosa, conducive to the repair of the gastric mucosa. There are mainly three kinds of drugs, one is colloidal bismuth such as aluminum phosphate gel; one is prostaglandin and its derivatives; and another is gefaltein, aluminum thioglycollate, etc. Second, drugs that inhibit the secretion of gastric acid, mainly lazoles, including omeprazole, rabeprazole, pantoprazole, drugs that inhibit gastric acid are often used in combination with drugs that protect the gastric mucosa for treatment. Third, drugs to promote gastrointestinal power, if the patient has gastrointestinal dysfunction, indigestion symptoms, you can eat some drugs to promote gastrointestinal power, such as morphine. Fourth, antibiotics, if the ulcer is caused by H. pylori infection, you need to take antibiotics, commonly used quadruple therapy includes an acid suppressant, a drug to protect the gastric mucosa and two antibiotics.