Acid reflux and heartburn may be caused by reflux esophagitis, hiatal hernia, chronic gastritis, gastric ulcer, etc. Acid suppressants, gastric motility stimulants, gastric mucosal protectants, antibiotics and other medications can be given according to the cause of reflux esophagitis, gastric ulcers, etc. or surgical treatment. 1. Reflux esophagitis: antacids such as omeprazole and rabeprazole can be given to promote gastric emptying and reduce reflux in combination with domperidone. 2. Esophageal hiatal hernia: give lansoprazole, mosapride and other medications, if the symptoms continue to be unrelieved recurrent attacks, can consider esophageal hiatal hernia repair, open surgical treatment. 3. Chronic gastritis: Ranitidine, omeprazole can be given to inhibit the secretion of gastric acid, the joint application of aluminum thioglycollate, aluminum phosphate gel, etc., to promote the repair of the gastric mucosa to improve the gastric reflux, heartburn. 4. Gastric ulcer: If infected with Helicobacter pylori can be given quadruple therapy, commonly used drugs are amoxicillin, clarithromycin, omeprazole, colloidal bismuth pectin and so on. If discomfort occurs, it is recommended to consult a doctor in a timely manner, under the guidance of the doctor to clarify the cause of the disease and targeted treatment, do not take medication on their own, so as not to delay the condition.